Products

Circadin®Circadin

Circadin® 2mg prolonged-release melatonin formulation, approved for use (up to 13 weeks) in treatment of primary insomnia characterized by poor quality of sleep in patients aged 55 years or over.

Circadin® has been approved by several agencies globally, including the European Medicines Agency (EMA), the Australian Therapeutic Goods Administration (TGA), the Swiss Agency for Therapeutic Products (SwissMedic) and the Israeli Ministry of Health (MOH). The approval is based on clinical studies demonstrating positive effects on sleep quality, sleep induction, and most importantly next day alertness and functioning. Read more

Slenyto® (“PedPRM”)

Slenyto® is an age-appropriate formulation of prolonged-release melatonin indicated for the treatment of insomnia in children and adolescents aged 2-18 with Autism Spectrum Disorder (ASD) and / or Smith-Magenis syndrome, where sleep hygiene measures have been insufficient (EMA/CHMP opinion).

The mini-tablet age appropriate formulation (prolonged – release, 3 mm diameter, film coated) was designed to facilitate swallowing for the ASD pediatric population, in response to the unmet medical need in treating insomnia in this population.Read more

Products in Clinical Phase

 Neu-P12

Neu-P12 is a multi-facetted new chemical entity with analgesic potential.
Its mechanism of action involves inhibition of human Nav1.7 sodium channels and TRPV1 non-selective cation channels that are widely expressed in skin tissues, and peripheral sensory nerve fibers. Neu-P12 does not interact with COX 1 or 2 or opioid receptors, suggesting a selective mode of action. It demonstrates a good potential for the treatment of inflammatory and pain in three different and relevant animal pain models.
Neu-P12 is intended as a therapy for neuropathic pain and is currently in Phase I at First in Human stage.

Products in Preclinical Phase

Neu-240

Neu-240 is a potent and selective uncompetitive NMDA receptor modulator aimed at improving motor control. Neu-240 is a derivative of Neu-120, intended for use as adjunct therapy to levodopa in patients with Parkinson’s disease and is currently at the preclinical stage.

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  • Circadin
  • Recent news

    • Slenyto (PedPRM) is now available in Norway!
    • Neurim Pharmaceuticals attends the ESCAP Congress in Vienna, Austria, 30 June – 2 July 2019
    • Slenyto (PedPRM) is now also available in Italy!
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